Efferon
Efferon NEO
Paediatric cytokine adsorption for hyperinflammation
A paediatric blood purification cartridge designed exclusively for children, targeting the broad cytokine cascade seen in hyperinflammatory states.
- Exclusively for paediatric patients
- Low-volume design for paediatric circuits
- Single-use, sterile cartridge
Overview
About this product
Efferon NEO is specifically designed and approved for paediatric patients. It is not an adult cartridge. Its compact format and low extracorporeal volume support blood purification in children whose deterioration is driven by a generalised inflammatory mediator load.
Its sorbent adsorbs a broad band of cytokines and other mid-molecular-weight molecules implicated in paediatric cytokine storm, hyperinflammatory syndromes and post-cardiotomy inflammatory response.
The cartridge is used in a paediatric extracorporeal circuit and may be run in series with continuous renal replacement therapy, allowing a single circuit to provide both solute clearance and mediator adsorption. Treatment must follow the paediatric instructions for use and local specialist protocol.
Features
Key features and benefits
Broad cytokine adsorption
Captures a wide band of mid-molecular-weight inflammatory mediators rather than a single target.
CRRT-compatible
Can be placed in series with paediatric renal replacement therapy to combine solute clearance and mediator removal.
Stable haemodynamics
Adsorption avoids the large fluid shifts associated with high-volume exchange techniques.
Paediatric circuit design
A compact cartridge format supports the low extracorporeal volumes required for children.
Clinical use
Applications and indications
Paediatric hyperinflammatory shock
Children with escalating vasopressor requirement and markedly raised inflammatory markers.
Paediatric post-cardiotomy inflammation
Systemic inflammatory response in children following cardiopulmonary bypass.
Other paediatric hyperinflammatory states
Selected non-infective hyperinflammatory conditions in children under specialist direction.
- Paediatric cytokine storm
- Paediatric hyperinflammation
- Paediatric multi-organ dysfunction
Specifications
Specifications, sizes and models
- Therapy
- Haemoperfusion — broad-spectrum adsorption
- Target molecules
- Cytokines and mid-molecular-weight mediators
- Patient group
- Paediatric patients only — not for adult use
- Circuit
- Paediatric circuit, standalone or in series with CRRT
- Anticoagulation
- Heparin or regional citrate per unit protocol
- Use
- Single use, sterile, single patient
Available sizes & models
Paediatric cartridge
Compact, low-volume format designed specifically for children
Paediatric series configuration
Pre- or post-filter placement with paediatric CRRT
Technical
Important technical information
- Efferon NEO is for paediatric patients only and must not be presented or used as an adult cartridge.
- Follow the specified priming protocol; incomplete priming can trap air in the sorbent bed.
- When run in series with CRRT, confirm circuit pressure limits before starting therapy.
- Monitor for adsorption of therapeutic drugs such as antimicrobials and adjust dosing with pharmacy input.
- Track platelet count and circuit pressures throughout the session.
- Single use only; replace the cartridge at the interval specified in the instructions for use.
This page is a clinical summary for healthcare professionals. Always refer to the manufacturer's instructions for use for full indications, contraindications, warnings and handling requirements.
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